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Vol. 5. Issue 1.
Pages 21-28 (January - February 1999)
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Vol. 5. Issue 1.
Pages 21-28 (January - February 1999)
Open Access
Resistência a corticosteroides*
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J. Pinto Mendes**
** Assistente Hospitalar Graduado de Imunoalergologia. Serviço de Pneumologia. Hosp. Univer Coimbra (Director: Prof. L. Cardoso Oliveira)
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BIBLIOGRAFIA
[1.]
B.W. Kirkham, M.M. Corkill, S.C. Davison, G.S. Panayi.
Response to glucorticoid treatment in rheumatoid arthritis: in vitro cell mediated immune assay predicts in vivo responses.
J. Rheumatol., 18 (1991), pp. 821-825
[2.]
G. Clark, T.M. Barrat.
Minimal change nephrotic syndrome and focal segmental glomerulosclerosis.
Paediatric Nephrology. Ed, 3 (1993), pp. 767-787
[3.]
E. Langhoff, K.K. Jacobsen, L.P. Ryder.
Recipient lymphocyte sensivity to methylprednisolone affects cadaver kidney graft survival.
Lancet, 1 (1986), pp. 1296-1297
[4.]
G.M. Norbiato, M. Bevilacqua, T. Vago.
Cortisol resistence in acquired immunideficiency syndrome.
J. Clin. Endocriol. Metab., 74 (1992), pp. 608-613
[5.]
H.J. Schwartz, F.C. Lowell, J.C. Malby.
Steroid resistence in bronchial asthma.
Ann. Int Med., 69 (1968), pp. 493-495
[6.]
J. Carmichael, I.C. Paterson, P. Diaz.
Corticosteroid resistance in chronic asthma.
B.M.J., 282 (1981), pp. 1419-1422
[7.]
E.R. Sher, D.Y.M. Leung, W. Surs.
Steroid resistant asthma: cellular mechanisms contributing to immediate response to glucocorticoid therapy.
J. Clin. Invest, 3 (1994), pp. 33-39
[8.]
T.H. Lee, R. Brattsand, D.Y.M. Leung.
Corticosteroid action and rcsistence in asthma.
Am. J. Respir. Cell Mol. Biol., 154 (1996), pp. S1-S79
[9.]
S.W.J. Lamberts, A.C.H. Gordon, J.C. Douglas.
Resistence to methylprednisolone in cultures of blood mononuclear cells from glucocorticoid resistant asthmatic patients.
Clin. Science., 97 (1984), pp. 698-706
[10.]
O.M. Hurley, A. Accili, A. Stratakis.
Point mutation causing a single aminoacid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance.
J. Cli. Invest., 87 (1991), pp. 680-686
[11.]
S.W.J. Lamberts, J.W. Kioper, F.H. Dejong.
Familial and iatrogenic cortisol receptor resistance.
J. Steroid. Biochem. Mol. Biol., 43 (1992), pp. 385-388
[12.]
S.J. Lane, J.P. Arm, D.Z. Staynon, T. Lee.
Chemical mutation analysis of the human glucocorticoid receptor cDNA in glucocorticoid-resistant bronchial asthma.
Am. J. Respir. Cell Mol. Biol, 11 (1994), pp. 42-48
[13.]
R.P. Wood II, H. Milgrom.
Vocal cordal disfunction.
J. Allergy. Clin. Immunol., 98 (1996), pp. 481-485
[14.]
S. Szefler.
Glucocorticoid therapy for asthma: clinical pharmacology.
J. Allergy Clin. Immunol., 88 (1991), pp. 147-165
[15.]
M.C. Polnansky, A.C.H. Gordon, J.C. Douglas.
Resistance to methylprednisolone in cultures of mononuclear cells from glucocorticoid resistant asthmatic patients.
Clin. Science, 67 (1984), pp. 639-645
[16.]
C.J. Corrigan, P. Brown, N.C. Barnes.
Glucocorticoid resistance in chronic asthma: glucocorticoid pharmacokinetics, glucocorticoid receptor characteristics and inhibition of peripheral blood T-cell proliferation by glucocorticoid in vitro.
Am. Rev. Respir. Dis, 144 (1991), pp. 1016-1025
[17.]
J. Alvarez, W. Surs, D.Y.M. Leung.
Steroidresistant asthma: immunologic and pharmacologic features.
J. Allergy. Cli. Immunol, 89 (1992), pp. 714-721
[18.]
S.J. Lane, A.R. Sousa, R.N. Poston, T.H. Lee.
In vivo cutaneous tuberculin response to prednisolone in corticosteroid resistant bronchial asthma.
J. Allergy Clin. Immunol., 97 (1996), pp. 698-706
[19.]
C.J. Corrjgan, P.H. Brown, N.C. Barnes.
Glucocorticoid resistance in chronic asthma: peripheral blood T lymphocyte activation and comparison of the T lymphocyte inhibitory effects of glucocorticoids and cyclosporin A.
Am. Rev. Respir. Dis., 143 (1991), pp. 1020-1024
[20.]
C.J. Corrigan, P.H. Brown, N.C. Barnes.
Glucocorticoid resistance in chronic asthma.
Am. J. Respir. Dis., 144 (1991), pp. 1016-1025
[21.]
S.J. Lane, T.H. Lee.
Glucocorticoid receptor characteristics in monocytes of patients with concosreroid-resistant bronchial asthma.
Am. Rev. Respir. Dis., 143 (1991), pp. 1020-1024
[22.]
E.R. Sher, D.Y.M. Leung, W. Surs.
Steroid-resistat asthma: cellular mechanisms contributing to inadquate response to gluco-corticoid therapy.
J. Clin. Invest., 93 (1994), pp. 33-39
[23.]
J.C. Kam, S.J. Szefler, W. Surs.
Combination of IL-2 and IL-4 reduces glucocorticoid-receptor binding affinity and T cell responses to glucocorticoids.
J. Immunol., 151 (1993), pp. 3460-3466
[24.]
D.Y.M. Leung, R.J. Martin, J. Szeflers.
Dysregulation of interleukin-4, interteukin-5 and intyerferon-gene expression in steroid’ resistant asthma.
J. Exp. Med., 181 (1995), pp. 33-40
[25.]
P.J. Barnes.
Molecular mechanisms of steroid action in man.
J. Allergy. Clin.lmmunol, 97 (1996), pp. 159-168
[26.]
P.J. Barnes, I.M. Adcock.
Transcription factors and asthma.
Eur. Respir. J., 12 (1998), pp. 221-234
[27.]
D.S. Latchman.
Transcription-factor mutations and disease.
N. Engl. J. Med., 334 (1996), pp. 28-33
[28.]
H.F. Yang Yen, J.C. Chambard, Y.L. Sun.
Transcriptional interference between c-Jan and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction.
Cell., 62 (1990), pp. 1205-1215
[29.]
M.J. Peters, I.M. Adcock, R.C. Brown, P.J. Barnes.
Beta-adrcnoceptor agonists interfere with glucocorticoid receptor DNA binding in rat lung.
Eur. J. Pharmacal., 289 (1995), pp. 275-281
[30.]
D.A. Stevens, P.J. Barnes, I.M. Adcock.
Bcta-agonists inhibits DNA binding of glucocorticoid receptors in human pulmonary and bronchial epithelial cells (Abstract).
AM. J. Respir. Crit. Care Med, 151 (1995), pp. 195
[31.]
I.M. Adcock, C.R. Brown, C.M. Gelder.
The effects of glucocorticoids on transcription factor activation in human peripherc1l blood mononuclear cells.
Am. J. Phisiol., 37 (1995), pp. C331-C338
[32.]
C.S. Wong, I. Wamedna, I.D. Pavord, A.E. Tattersfleld.
Effect of glucocorticoids on transcription factor activation in human peripheral blood mononuclear cells.
Am. Physiol, 37 (1995), pp. C331-C338
[33.]
P.J. Barnes, I.M. Adcock.
NF-kB: a pivotal role in asthma and a new target for therapy.
Trends Pharmacal. Sc., 18 (1997), pp. 46-50
[34.]
U. Siebenlist, G. Franzuso, R. Brown.
Structure, regulation and function of NF-kB.
Annu. Rev. Cell. Biol., 10 (1994), pp. 405-455
[35.]
Q. Xie, Y. Kashiwarbara, C. Nathan.
Role of transcription factor Nf-kB/Rel in induction of nitric oxide synthase.
J. Biol. Chem., 269 (1994), pp. 4705-4708
[36.]
J.M. Adcock, S. Brady, S. Lim.
Increase JUN kinase activity in peripheral blood monocytes from steroidresistant asthmatic subjects (Abstract).
Am. Rev. Respir. Crit. Care Med., 155 (1997), pp. 288
[37.]
J.M. Adcock, C.R. Brown, C.M. Gelder.
The effects of phorbol ester and cytokine stimulated transcription factor activation in human lung.
Life Sci., 55 (1994), pp. 1147-1153
[38.]
I.M. Adcock, C.R. Brown, H. Shiasaki, P.J. Barnes.
Effects of dexamethasone on cytokine and phorbol ester stimulated c-Fos and c-Jun DNA binding and gene expression in human Lung.
Eur. Respir. J., 7 (1994), pp. 2117-2123
[39.]
V. Macek, J. Sorv, S. Korpriva, P.J. Marin.
Persistent adenovirus infection and chronic airway obstruction in children.
Am. J. Respir. Crit. Care Med., 150 (1994), pp. 7-10
[40.]
H.L.C. Beynon, N.D. Garbet, P.J. Barnes.
Severe premenstrual exacerbations of asthuma: effects of intramuscular progesterone.
Lancet, 2 (1988), pp. 370-372
[41.]
E. Kalkhoveng, E.S. Wissink, P.T. Vander Saag, B. Van Der Burg.
Negative intection between the Ret A (p65) sub-unit of NF-kB and the progesterone receptor.
J. Biol. Chem., 271 (1996), pp. 6217-6224
[42.]
O. Selroos, A. Pietinalho, A.-B. Lofros, A. Riska.
High dose is more effective than low-dose inhaled corticosteroids when starting medication in patients with moderately severe asthma (abstract).
Am. J. Respir. Crit. Care Med, 155 (1997), pp. 349
[43.]
I.M. Adcock, P.J. Barnes.
Ligand- induced differentiation of glucocorticoid receptor (GR) transrepression and transactivation (Abstract).
Am. J. Respir. Crit. Care Med, 153 (1996), pp. 243
[44.]
B.M. Vayssiere, S. Dupont, A. Choquart.
Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit anti-inflammatory activity in vivo.
Mol. Endocrinel., 11 (1997), pp. 1245-1255
[45.]
S. Heck, M. Kullman, A. Grast.
A distinct modulation domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.
EMBO J, 13 (1994), pp. 4087-4095
[46.]
R. Schrek, P. Rieber, P.A. Baeurie.
Reactive oxygen intermediates as apparently widely used messenger in the activation of the NF-kB transcription factor and HIV-1.
EMBO J, 10 (1991), pp. 2247-2258
[47.]
T. Myajima, V. Kotare.
Spine trapping agent, phenyl N-ter-butyl nitrone, inhibits induction of nitric oxide synthase in endoxin-induced shock in mice.
Biochem. Biophys. Res. Commun., 215 (1995), pp. 114-121
[48.]
P. Wang, P. Wu, M.J. Spiegel.
Interleukin (LL) -10 inhibits nuclear factor kB activation in human monocytes. IL-10 and IL-4 supress cytokine synthesis by different mechanisms.
J. Bioi. Chern, 270 (1995), pp. 9558-9563
[49.]
H.L. Pahl, B. Krauss, K. Schultze-Osthoff.
The immunossupressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kB.
J. Exp. Med., 183 (1996), pp. 1829-1840
[50.]
A. Yaron, H. Gonen, I. Alkalai.
Inhibition of NF-kB cellular function via specific targeting of the IkB ubiquitin ligase.
EMBO. J., 16 (1997), pp. 6486-6494
[51.]
L.C. Wright, S. Cammisuli, L. Baboulene.
Cyclosporin A and glucocorticoids interact synergistically in T lymphocytes: implications for asthma therapy.
Am. J. Respir. Crit. Care Med, 151 (1995), pp. 675

Trabalho apresentado em painel sobre "Resistencia a Fármacos" no XIV Congresso de Pneumologia (Viseu, 10.11.98)

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