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Vol. 10. Issue 5.
Pages 421-430 (September - October 2004)
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Vol. 10. Issue 5.
Pages 421-430 (September - October 2004)
CASO CLÍNICO/CLINICAL CASE
DOI: 10.1016/S0873-2159(04)05015-9
Open Access
Tumor solitário fibroso – a propósito de dois casos clínicos
Solitary fibrous tumor – two cases report
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Gabriela Fernandes1, Ana Sofia Barroso1, Carmen Valbuena2, Ana R. Santos3
1 Interna Complementar de Pneumologia. Serviço de Pneumologia do Hospital de São João.
2 Assistente Hospitalar de Anatomia Patológica. Serviço de Anatomia Patológica do Hospital de São João.
3 Assistente Hospitalar de Pneumologia. Serviço de Pneumologia do Hospital de São João.
Article information
RESUMO

O tumorsolitário fibroso é uma neoplasia rara, derivada de células mesenquimatosas que necessita para o diagnóstico definitivo do recurso à análise imuno-histoquímica. A maioria destes tumores é benigna, sendo o tratamento de eleição, quer para as variantes benignas quer malignas, a ressecção cirúrgica completa. No entanto, por estarem descritas recidivas locais e/ou à distância, devem manter-se estes doentes sob vigilância apertada, sendo inadequado encarar estas lesões como definitivamente benignas. Os autores fazem uma breve revisão da clínica, características radiológicas, achados histológicos e opções terapêuticas e relatam dois casos clínicos, discutindo as diferenças entre eles.

REV PORT PNEUMOL 2004; X (5): 421-428

Palavras-chave:
Tumor solitário fibroso
intra-torácico
imuno-histoquímica
ABSTRACT

Solitary fibrous tumor is a rare neoplasm derived from mesenchymal cell. To achieve a diagnosis and to differentiate from others neoplasm immunohistochemical analysis is needed. The majority of these tumours are benign, and complete surgical resection remains the mainstay of therapy for both the benign and malignant variants. However, there are cases of local and distant recurrences, so patients should have a close follow-up and it is far incorrect to look at this lesion as definitely benign. The authors review clinical presentation, radiological features, histological findings, and treatment options for this tumor and report two clinical cases discussing the differences between them.

REV PORT PNEUMOL 2004; X (5): 421-428

Key-words:
Solitary fibrous tumour
intrathoracic
immunochemistry
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BIBLIOGRAFIA
[1.]
J.S. Gold, C.R. Antonescu, C. Hadju, C.R. Ferrone, M. Hussain, J.J. Lewis, M.F. Brennan, D.G. Coit.
Clinicopathologic correlates of solitary fibrous tumors.
Cancer, 94 (2002), pp. 1057-1068
[2.]
G. Cardillo, F. Facciolo, A. Cavazzana, G. Capece, R. Gasparri, M. Martelli.
Localized (Solitary) Fibrous Tumors of the Pleura:An Analysis of 55 Patients.
Ann Thoracic Surg, 70 (2000), pp. 1808-1812
[3.]
S. Suster, A.G. Nascimento, M. Miettinen, J.Z. Sickel.
Moran CA Solitary Fibrous Tumors of Soft Tissue – a Clinicopathologic and Immunohistochemical Study of 12 Cases.
Am J Surg Pathol, 19 (1995), pp. 1257-1266
[4.]
M. Van De Rijn, C.M. Lombard, RVl. Rouse.
Expression of CD34 by Solitary Fibrous Tumors of the Pleura, Mediastinum, and Lung.
Am J Surg Pathol, 18 (1994), pp. 814-820
[5.]
A. Vallat-Decouvelaere, S.M. Dry, C.D.M. Fletcher.
Atypical and Malignant Solitary Fibrous Tumors in Extrathoracic Locations – Evidence of their Comparability to Intrathoracic Tumors.
Am J Surg Pathol, 22 (1998), pp. 1501-1511
[6.]
M. Briselli, E.J. Mark, R. Dickersin.
Solitary Fibrous Tumor of the Pleura: Eight new Cases and a Review of 360 Cases in the Literature.
Cancer, 47 (1981), pp. 2678-2689
[7.]
S.Z. Ali, V. Hoon, S. Hoda, R. Heelan, Zakowski.
Solitary Fibrous Tumor – A Cytologic-Histologic Study with Clinical, Radiologic and Imunohistochemical correlations.
Cancer, 81 (1997), pp. 116-121
[8.]
D.M. England, L. Hochholzer, M.J. Mccarthy.
Localized Benign and Malignant Fibrous Tumors of the Pleura – A Clinicopathologic Review of 223 Cases.
Am J Surg Pathol, 13 (1989), pp. 640-658
[9.]
R.H. Sandvliet, M. Heysteeg, M.A.A. Paul.
Large Thoracic Mass in a 57- Year- Old – Patient.
Chest, 117 (2000), pp. 897-900
[10.]
S. Brozzetti, N. Dándrea, M.R. Limiti, M.C. Pisanelli, R. de Angelis, A. Cavallaro.
Clinical behaviour of solitary fibrous tumors of the pleura. An immunohistochemical study.
Anticancer Res, 20 (2000), pp. 4701-4706
[11.]
D. Scharifker, M. Kaneko.
Localized Fibrous “Mesothelioma” of the Pleura (Submesothelial Fibroma).
Cancer, 43 (1979), pp. 627-635
[12.]
M. De Perrot, A.M. Kurt, J.H. Robert, B. Borisch.
Spiliopoulos A Clinical behaviour of solitary fibrous tumors of the pleura.
Ann Thorac Surg, 67 (1999), pp. 1456-1459
[13.]
B.W. Witkin, J. Rosia.
Solitary Fibrous Tumor of the Mediastinum. A report of 14 cases.
Am J Surg Pathol, 13 (1989), pp. 547-557
Copyright © 2004. Sociedade Portuguesa de Pneumologia/SPP
Pulmonology

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