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Vol. 11. Issue 4.
Pages 407-412 (July - August 2005)
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Vol. 11. Issue 4.
Pages 407-412 (July - August 2005)
Caso Clínico\Clinical Case
Open Access
Tromboembolismo pulmonar associado a infecção VIH
Pulmonary embolism associated to HIV infection
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Nuno Germano*, Paula Mendonça**, António Murinello**
* Interno do Internato Complementar de Medicina Interna, Hospital de Curry Cabral, Lisboa
** Assistente Hospitalar Graduada(o) de Medicina Interna, Hospital de Curry Cabral, Lisboa
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Resumo

A presença de anticorpos antifosfolípidos é frequente em doentes com infecção VIH principalmente em fases avançadas da doença. Apesar da elevada prevalência de anticorpos antifosfolípidos, a sua associação a fenómenos trombóticos é rara, estando apenas descritos alguns casos.

Os autores apresentam um caso clínico cuja manifestação inaugural de uma infecção VIH foi um tromboembolismo pulmonar associado à presença de anticoagulante lúpico.

Rev Port Pneumol 2005; XI (4): 407-412

Palavras-chave:
Anticorpos antifosfolípidos
infecção VIH e tromboembolismo pulmonar
Abstract

Antiphospholipid antibodies are frequently found in patients with HIV infection mainly in advanced forms of disease. Despite its elevated prevalence the association with thrombotic events is rare.

The author present a clinical case of a HIV patient in which the frist manifestation of the disease was a pulmonary embolism.

Rev Port Pneumol 2005; XI (4): 407-412

Key words:
Antiphospholipid antibodies
HIV infection and pulmonary embolism
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Bibliografia
[1.]
M. Khanashta, G. Hughes.
Antiphospholipid antibodies and antiphospholipid syndrome.
Curr Opin Rheumatol, 7 (1995), pp. 389-394
[2.]
R. Asherson, A. Cervera.
Antiphospholipid antibodies and infections.
Ann Rheum Dis, 62 (2003), pp. 388-393
[3.]
M. Ramos Casals, J. Font, M. Ingelmo.
Prevalence and clinical significance of hepatitis C virus infection in systemic autoimmune diseases].
Med Clin, 116 (2001), pp. 70-79
[4.]
R. Asherson, Y. Shoenfeld.
Human immunodeficiency virus infection, antiphospholipid antibodies, and the antiphospholipid syndrome.
J Reumatol, 30 (2003), pp. 214-219
[5.]
E. Bloom, D. Abrams, G. Rodgers.
Lupus anticoagulant in the acquired immunodeficiency syndrome.
JAMA, 256 (1986), pp. 491-493
[6.]
M. Cappel, T. Simon, M. Tiku.
Splenic infraction associated with anticardiolipin antibodies with acquired immunodeficiency syndrome.
Dig Dis Sci, 38 (1993), pp. 1153-1156
[7.]
J. Sergent.
Vasculitis associated with viral infection.
Clin Rheum Dis, 6 (1980), pp. 339-350
[8.]
M. Ramos-Casals, R. Cervera, M. Lagrutti, et al.
Clinical features related to antiphospholipid syndrome in patients with chronic viral infection (Hepatitis C vírus/HIV infection): description of 82 cases.
Clinic Infections Diseases, 38 (2004), pp. 1009-1016
[9.]
R. Canoso, L. Zon, J. Groopman.
Anticardiolipin antibodies associated with HTLV-III infection.
British Journal of Haematology, 65 (1987), pp. 495-498
[10.]
Cohen A, Philips T, Kienler C. Circulating coagula-tion inhibitors in the acquired immunodeficiency syndrome. Annals of Internal Medicine 102: 800-13.
[11.]
J. Guerin, E. Casey, C. Feighery, J. Jackson.
Anti b2 GP1 antibody isotype and Ig subclass in antiphospholipid syn drome patients.
Autoimmunity, 31 (1999), pp. 109-116
[12.]
L. Stahl, C. Wiedman, T. Spira, G. Hixon, B. Evatt.
Potein S deficiency in men with long-term human immunodeficiency virus infection.
Blood, 81 (1993), pp. 1801-1807
[13.]
S. Tigges, R. Meli.
Osteonecrosis with HIV infection.
Can Assoc Radiol J, 46 (1995), pp. 280-304
[14.]
J. Rademaker, J. Dobro, G. Solomon.
Osteonecrosis and human immunodeficiency virus infection.
J Rheumatol, 24 (1997), pp. 601-604
[15.]
A. Scribner, P. Troia-Cancio, B. Cox, D. Marcantonio, F. Hanid, P. Keiser, et al.
Osteonecrosis in HIV: a casecontrol study.
J Acquir Immun def Syndr, 25 (2000), pp. 19-25
[16.]
P. Monier, K. Mekown, M. Bronze.
Osteonecrosis complicating Highly Active Antiretroviral Therapy in patients infected with Human Immunodeficiency virus.
Clin Infect Dis, 31 (2003), pp. 1488-1492
[17.]
S. George, S. Swindells, R. Knudson, J. Stapleton.
Unexplained thrombosis in HIV-infected patients receiving protease inhibitors: Report of seven cases.
Am J Med Sci, 107 (1999), pp. 624-626
[18.]
S. Shanhnaz, G. Parikh, A. Opran.
Antiphospholipid antibody syndrome manifesting as a deep venous trombosis and pulmonary embolism in a patient with HIV.
Am J Med Sci, 327 (2004), pp. 231-232
[19.]
C. Rouzioux, A. Aymard, B. Pehosse, M. Eliasceiwicz, J. Frottier.
Cerebral Venous thrombosis and dual primary infection with human immunodeficiency virus and cytomegalovirus.
Journal of Neurology, Neurosurgery and Psychiatry, 52 (1989), pp. 1010-1016
[20.]
M. Belmonte, R. Garcia-Portales, I. Doménech, A. Fernandez-Nebro, M. Camps, E. Ramón.
Avascular necrosis of boné in human immunideficiency vírus infection and anthiphospolipid antibodies.
J Rheumatol, 20 (1993), pp. 1425-1428
[21.]
M. Karmochkine, A. Ankri, V. Calvez, et al.
Plasma Hypercoagulability is correlated to plasma HIV loadthrombos Hemostas, 80 (1998), pp. 208-209
[22.]
S.E. Fepper, R.I. Fox, M.M. Orsen, et al.
Thrombotic Tendencies and correlation with clinical status in patients infected with HIV.
South Med J, 88 (1995), pp. 1126-1130
Copyright © 2005. Sociedade Portuguesa de Pneumologia/SPP
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