Journal Information
Vol. 15. Issue 2.
Pages 313-318 (March - April 2009)
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Vol. 15. Issue 2.
Pages 313-318 (March - April 2009)
Caso Clínico/Case Report
Open Access
Alveolite alérgica extrínseca com expressão imunológica atípica
Extrinsic allergic alveolitis with an atypical immune expression
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Teresa Costa1, Cidália Rodrigues1, Ana Arrobas2
1 Interna do Complementar de Pneumologia
2 Assistente Hospitalar Graduada de Pneumologia
Article information
Resumo

A alveolite alérgica extrínseca e a sarcoidose são ambas doenças granulomatosas pulmonares que se caracterizam pela presença de granulomas não necrotizantes. Ambas apresentam alterações típicas no lavado broncoalveolar, com relações CD4/CD8 opostas. No entanto, a sarcoidose não apresenta hoje em dia factores etiológicos bem definidos, como a alveolite alérgica extrínseca. As autoras apresentam dois casos clínicos com curso clínico, imagiológico, funcional e imunológico semelhante, embora com confirmação histopatológica não concordante com as alterações do LBA e com a particularidade de pertencerem a dois elementos da mesma família, convivente, e de terem surgido com poucas semanas de intervalo.

Rev Port Pneumol 2009; XV (2): 313-318

Palavras-chave:
Alveolite alérgica extrínseca
pneumonia de hipersensibilidade
sarcoidose
Abstract

Extrinsic allergic alveolitis and sarcoidosis are two granulomatosis of the lung characterized by non-necrotizing granuloma. Both have typical bronchoalveolar lavage immunology, with opposite CD4/CD8 relation. However, sarcoidosis does not have such well defined etiology as extrinsic allergic alveolitis. The authors present two cases with similar clinical course, imagiology, lung function and immunology, although they both had an histology that was not concordant with the bronchoalveolar lavage, and with the peculiarity of being two elements of the same family, co-inhabitants and with a clinical presentation only a few weeks apart.

Rev Port Pneumol 2009; XV (2): 313-318

Key-words:
Extrinsic allergic alveolitis
hypersensitivity pneumonitis
sarcoidosis
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Bibliografia
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Copyright © 2009. Sociedade Portuguesa de Pneumologia/SPP
Pulmonology

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