Cost-effectiveness of IGRA/QFT-Plus for TB screening of migrants in Oman

https://doi.org/10.1016/j.ijid.2020.03.010Get rights and content
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Abstract

Objective

To estimate the cost of a screening program for identifying latent tuberculosis (TB) infections in migrants to Oman.

Methods

A Markov model was used to estimate the cost of screening using an interferon-gamma release assay (IGRA) applied to all migrants from high TB endemic countries, followed by preventive TB treatment.

Results

The model compared seven different scenarios, with a comparison of the direct cost and the quality-adjusted life-years (QALYs) saved.

Conclusions

IGRA testing followed by 3 months of preventive treatment with rifapentine/isoniazid (3HP) was the most cost-effective intervention.

Keywords

Latent tuberculosis
Screening
Cost
DAILYs

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