Clinical studyDecreased hypoxic ventilatory drive in the obesity-hypoventilation syndrome☆
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Effectiveness of CPAP vs. Noninvasive Ventilation Based on Disease Severity in Obesity Hypoventilation Syndrome and Concomitant Severe Obstructive Sleep Apnea
2022, Archivos de BronconeumologiaCitation Excerpt :Roughly 90% of patients with OHS have concomitant obstructive sleep apnea (OSA),2 with 73% having severe OSA.3 Compared with eucapnic OSA4,5 and eucapnic obese,6,7 patients with OHS have a higher prevalence of cardiovascular and respiratory morbidity resulting in increased hospitalization risk, greater healthcare resource utilization, and augmented mortality.7–16 Ambulatory patients with OHS are typically treated with nocturnal positive airway pressure (PAP) therapy during sleep such as noninvasive ventilation (NIV), usually with bilevel pressure settings, or continuous positive airway pressure (CPAP).
Obesity Hypoventilation: Traditional Versus Nontraditional Populations
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2020, Obesity Hypoventilation Syndrome: From Physiologic Principles to Clinical PracticePerioperative considerations and management in patients with obesity hypoventilation syndrome
2020, Obesity Hypoventilation Syndrome: From Physiologic Principles to Clinical PracticeThe pathophysiology of obesity hypoventilation syndrome
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This study was supported by National Institutes of Health Program Project Grant HL-14985-03 and Intensive Respiratory Care and Rehabilitation Grant HL-04933, Bethesda, Maryland.
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From the Cardiovascular Pulmonary Research Laboratory and Pulmonary Division of the Department of Medicine, University of Colorado Medical Center, Denver, Colorado.
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Present address: Mercy Hospital, Birmingham, Alabama.
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Present address: U.S. Army Medical Corps, Bremen, Germany.
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Recipient of Research Career Development Award.