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RESUMO
Nos últimos 10 anos, o número de publicações sobre o óxido nítrico tem crescido de um modo exponencial, em várias áreas da Medicina.
O que torna esta molécula tão atractiva, no âmbito da Pneumologia e da Imunoalergologia, é a evidência crescente de que a sua medição no ar expirado possa traduzir, de urn modo não invasivo, o grau de inflamação existente em várias doenças pulmonares.
O presente artigo, pretende realçar a importância dada recentemente ao papel do óxido nítrico como marcador de inflamação em doenças respiratórias, incidindo especialmente sobre a asma, a doença pulmonar obstrutiva crónica, a fibrose quística, as bronquiectasias, as infecções respiratórias, a alveolite fibrosante e a sarcoidose.
REV PORT PNEUMOL 2000; VI (4): 309-318
Palavras-chave:
NO
Asma
Doença Pulmonar Obstrutiva Crónica
DPOC
Fibrose Quística
Bronquiectasias
Infecções respiratórias
Alveolite Fibrosante
Sarcoidose
ABSTRACT
In the last 10 years, the number of publications about nitric oxide has increased enormously, covering many fields of medicine.
What makes this molecule so attractive for pneumologists and immunoallergologists, is the growing evidence that exhaled nitric oxide measurements might reflect, in a non-invasive way, the status of inflammation in several respiratory diseases.
This paper draws the attention to the role of nitric oxide as a marker of inflammation in respiratory diseases, especially regarding asthma, chronic obstructive pulmonary disease, cystic fibrosis, bronchiectasis, respiratory Infections, fibrosing alveolitis and sarcoidosis.
REV PORT PNEUMOL 2000; VI (4): 309-318
Key-words:
NO
Asthma
Chronic Obstructive Pulmonary Disease
COPD
Cystic Fibrosis
Bronchiectasis
Respiratory infections
Fibrosing alveolitis
Sarcoidosis
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