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Vol. 4. Issue 6.
Pages 617-623 (November - December 1998)
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Vol. 4. Issue 6.
Pages 617-623 (November - December 1998)
ARTIGO DE REVISÃO/REVIEW ARTICLE
Open Access
Um perfil clínico da pneumonia estafilocócica em toxicómanos
A Clinical Profile of Staphylococal Pneumonia on drug addicts
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Cheong Tak Hong1, Isabel Mesquita2, Nelson Diogo3
1 Assistente Hospitalar de Pneumologia no Centro Hospitalar Conde S. Januário em Macau.
2 Assistente Hospitalar Graduada de Pneumologia no Centro Hospitalar Conde S Januário em Macau
3 Assistente Hospitalar Graduado de Pncumologia e Rcsponsavel do Serviço de Pncumologia do Centro Hospitalar Conde S. Januário em Macau
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RESUMO

Objectivo: rever o perfil clínico dos doentes com Pneumonia por Staphylococcus aureus no Serviço de Pneumologia do Centro Hospitalar Conde S. Januário.

Desenho: análise retrospectiva.

Métodos: foram revistos os processos clínicos e radiológicos bem como os resultados bacteriológicos e a resposta à terapêutica de todos OS doentes internados, num Serviço de Pneumologia, com o diagnóstico de pneumonia por estafilococos, durante o pertodo compreendido entre 1991 e 1994.

Resultados: um total de 10 doentes, todos do sexo masculino, com uma média de idades de 27,9 anos (16-34), como diagnóstico de pneumonia estafilocócica foram analisados. Todos eles (100%) eram toxicomanos por via parentérica. Tosse, dispneia, febre, astenia e anorexia foram as manifestações clínicas predominantes. Infiltrados bilaterais multiplos e pneumatocelos, na radiografia de tórax, ocorreram em todos os doentes. Três doentes tiveram como complicação endocardite, três com pneumotórax, dois com derrame pleural, dois com insuficiência renal aguda e um com insuficiência hepática. O Staphylococcus aureus foi isolado em hemoculturas de todos (10/10) os doeotes e em expectoração de apenas dois (2/4). Todas as estirpes eram sensíveis aos derivados semi-sintéticos da penicilina. Todos os doentes registaram desaparecimento da sintomatologia e melhoria radiológica após antibioterapia.

Conclusões: os toxicómanos que utilizem a via parentérica constituem um grupo de risco para bacteriémia estafilocóciu, infecção da valvula tricuspida e pneumonia bilateral.

REV PORT PNEUMOL 1998; IV (6): 617-623

Palavras-chave:
Staphylococcus aureu
Toxicómano
Pneumonia
Endocardite
Penicilina semi-sintética
ABSTRACT

Obiective: To review the clinical profile of patients with Pneumonia due to Staphylococcus aureus at the Pneumology Service of Centro Hospitalar Conde S. Januário.

Design: A retrospective analysis.

Methods: The case notes, the chest radiographs, the microbiology results and the response to therapy of patients with staphylococcus pneumonia, admitted at the hospital for a period 1991-1994, were reviewed.

Results: A total of 10 males patients, with mean age 27,9 year (range 16 to 34 years) were notified as having staphylococcus pneumonia between 1991 and 1994. All of them (100%) were intravenous drug addicts. Cough, dyspnea, fever, fatigue and anorexia were the predominant clinical manifestations. Multiple bilateral infiltrates and pneumatoceles on the chest radiograph occurred on all of the patients. 3 patients were complicated with endocarditis, 3 with pneumothorax, 2 with pleural effusion, 2 with acute renal failure and one with liver failure. The staphylococcus aureus was isolated from the blood culture in all patients (10/10) and 2 (2/4) from the sputum cultures. All strains were semisyntetic penicillins sensible. All the patients had complete resolution of the symptoms and improvement in the chest radiograph fandings after antibiotic therapy.

Conclusions: Drug addicts who use parenteral routes are especially prone to Staphylococcal bacteremia, tricuspid valve infection, and bilateral pneumonia.

REV PORT PNEUMOL 1998; IV (6): 617-623

Key-words:
Staphylococcus aureus
Drug addicts
pneumonia
endocardites
Semisyntetic penicillin
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Copyright © 1998. Sociedade Portuguesa de Pneumologia/SPP
Pulmonology
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