Journal Information
Vol. 8. Issue 4.
Pages 315-327 (July - August 2002)
Share
Share
Download PDF
More article options
Vol. 8. Issue 4.
Pages 315-327 (July - August 2002)
ARTIGO ORIGINAL/ORIGINAL ARTICLE
Open Access
Tuberculose miliar
Miliary tuberculosis
Visits
9580
Gonçalo Salvado1, Cristina Santos2, Mota André3, Carlos Gomes3, Nelson Diogo3, Manuela Marques3, Jaime Pina4
1 Interno do Internato Complementar de Pneumologia
2 Assistente Hospitalar de Pneumologia
3 Assistente Hospitalar Graduado de Pneumologia
4 Chefe de Serviço de Pneumologia
This item has received

Under a Creative Commons license
Article information
RESUMO

Actualmente, Tuberculose Miliar (TM) designa todas as situações de doença progressiva resultantes da disseminação hematogénea maciça do Mycobacterium tuberculosis.

O autor apresenta um estudo retrospectivo que analisa as características clínico-epidemiológicas de 23 doentes internados com TM numa Unidade de Tuberculose dum hospital central, no período compreendido entre Abril de 1999 e Novembro de 2001. Cerca de 78% da população em estudo estava infectada com o Vírus da Imunodeficiência Humana, situando-se a média etária nos 37,7±13,1 anos.

Os dados apresentados alertam para a dificuldade diagnóstica da TM, nomeadamente em doentes de risco, e para a necessidade de desencadeamento de mecanismos de diagnóstico eficazes.

REV PORT PNEUMOL 2002; VIII (4): 315-327

Palavras-chave:
Tuberculose Miliar
epidemiologia
VIH
toxicodependência
ABSTRACT

Now a days, Miliary Tuberculosis (TM) refers to all forms of progressive disease resulting from massive dissemination of Mycobacterium tuberculosis.

This is a retrospective analysis of all TM cases in a Tuberculosis Unit of a Central Hospital between April 1999 and November 2001.

The mean age was 37,7±13,1years and 78% were Human Immunodefiency Virus co-infected patients.

The results show the difficulty in the diagnosis of TM and alert for correct diagnostic methods.

REV PORT PNEUMOL 2002; VIII (4): 315-327

Key-words:
Miliary Tuberculosis
epidemiology
HIV
drug addicts
Full text is only aviable in PDF
BIBLIOGRAFIA
[1.]
S.A. Sahn, T.A. Neff.
Miliary tuberculosis.
Am J Med, (1974), pp. 56-495
[2.]
M.D. Nesli Basgoz.
Pathogenesis and epidemiology of miliary tuberculosis, (2001), pp. 1-6
[3.]
D. Waagner.
The clinical presentation of tuberculous disease in children.
Pediatr Ann, (1993), pp. 22-622
[4.]
A.R. Hill, S. Premkumar, S. Brustein, et al.
Disseminated tuberculosis in the acquired immunodeficiency syndrome era.
Am Rev Respir Dis, (1991), pp. 144-1164
[5.]
J. Pina.
A tuberculose na viragem do milénio, 1, Lidel, (2000), pp. 4-575
[6.]
L.E. Morano Amado, L. Amador Barciela, A. Rodriguez Fernandez, et al.
Extracorporeal shock wave lithotripsy complicated with miliary tuberculosis.
[7.]
M. Federmann, H.K. Kley.
Miliary tuberculosis after extracorporeal shock-wave lithotripsy [letter].
N Engl J Med, (1990), pp. 323-1212
[8.]
H. Yekanath, P.A. Gross, J.H. Vitenson.
Miliary tuberculosis following ureteral catheterization.
[9.]
C.H. Anyanwu, E. Nassau, M. Yacoub.
Miliary tuberculosis following homograft valve replacement.
Thorax, (1976), pp. 31-101
[10.]
W.Y. Qunibi, M.B. Al-Sibai, S. Taher, et al.
Mycobacterial infection after renal transplantation-report of 14 cases and review of the literature.
Q J Med, (1990), pp. 77-1039
[11.]
R.A. Miller, L.A. Lanza, J.N. Kline, et al.
Mycobacterium tuberculosis in lung transplant recipients.
Am J Respir Crit Care Med, (1995), pp. 152-374
[12.]
D. Schlossberg.
Tuberculosis and nontuberculous mycobacterial infections, 4, pp. 271-284
[13.]
M.M. Braun, T.R. Cote, C.S. Rabkin.
Trends in death with tuberculosis during the AIDS era.
JAMA, (1993), pp. 269-2865
[14.]
K. Brudney, J. Dobkin.
Resurgment tuberculosis in New York City: Human immunodeficiency virus, homelessness and the decline of tuberculosis control programs.
Am Rev Respir Dis, (1991), pp. 144-745
[15.]
M.L. Antunes, J.A. Dias, A.F. Antunes, M.F. Pereira, E. Raymundo, M.F. Rodrigues.
Anti-tuberculosis drug resistance in Portugal.
Int J Tuberc Lung Dis, 4 (2000), pp. 223-231
[16.]
R.W. Shafer, D.S. Kim, J.P. Weiss, J.M. Quale.
Extrapulmonary tuberculosis in patients with human immunodeficiency virus infection.
Medicine (Baltimore), (1991), pp. 70-384
[17.]
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 5-1999. A 37-year-old man with ferver and difuse lymphadenopathy [clinical conference].
N Engl J med, (1999), pp. 340-545
[18.]
Lado F.L. Lado, E.B. Gomez, E.C. Arceo, C. Ortiz, A. Barron.
Clinical presentation of tuberculosis and the degree of immunodefiency in patients with HIV infection.
Scand J Infect Dis, (1999), pp. 31-387
[19.]
J.G. Bartlett.
The Johns Hopkins Hospital 2000-2001 - Guide to medical care of patients with HIV infection, 9, pp. 1-232
[20.]
F.G. Arthur, et al.
Miliary tuberculosis.
Am Rev Respir Dis, (1973), pp. 1327-1333
[21.]
C. Ribeiro, N. Diogo, L. Carreiro, I. Redol, F. Dias, J. Pina.
Tuberculose miliar – Revisão clínica e bibliográfica.
Arq. Soc. Port. Pat. Resp, (1986), pp. 15-28
[22.]
G. Maartens, P.A. Willcox, S.R. Benatar.
Miliary tuberculosis: Rapid diagnosis, hematologic abnormalities, and outcome in 109 treated adults.
Am J Med, (1990), pp. 89-291
[23.]
A.F. Gelb, C. Leffler, A. Brewin, et al.
Miliary tuberculosis.
Am Rev Respir Dis, 108 (1973), pp. 1327
[24.]
R.E. Slavin, T.J. Walsh, A.D. Pollack.
Late generalised tuberculosis: a clinical pathologic analysis and comparison of 100 cases in the preantibiotic and antibiotic eras.
Medicine (Baltimore), (1980), pp. 59-352
[25.]
M.D. Nesli Basgoz.
Clinical manifestations, diagnosis and treatment of miliary tuberculosis, (2001), pp. 1-10
[26.]
R.C. Rietbroek, R.P. Dahlmans, F. Smedts, et al.
Tuberculosis cutis miliaris disseminata as a manifestation of miliary tuberculosis: literature review and report of a case of recurrent skin lesions.
Rev Infect Dis, (1991), pp. 39-699
[27.]
C.B. Chapman, C.M. Whorton.
Acute generalized miliary tuberculosis in adults. A clinicalpathological study based on sixty-three cases diagnosed at autopsy.
N Engl J Med, (1946), pp. 235-239
[28.]
J.H. Kim, A.A. Langston, H.A. Gallis.
Miliary tuberculosis:epidemiology, clinical manifestations, diagnosis and outcome.
Rev Infect Dis, (1990), pp. 12-583
[29.]
R.J. Optican, A. Ost, C.E. Ravin.
High-resolution computed tomography in the diagnosis of miliary tuberculosis.
[30.]
A.E. Voloudaki, et al.
HRCT in miliary lung disease.
Acta Radiol, (1999), pp. 40-451
[31.]
K.S. Lee, et al.
Diffuse micronudular lung disease: HRTC and patologic findings.
J Comut Assist Tomogr, (1999), pp. 23-99
[32.]
P.M. Small, G.F. Schecter, P.C. Goodman, et al.
Treatment of tuberculosis in patients with advanced human immunodefiency virus infection.
N Engl J Med, (1991), pp. 224-289
Copyright © 2002. Sociedade Portuguesa de Pneumologia/SPP
Pulmonology
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?