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Vol. 6. Issue 3.
Pages 195-204 (May - June 2000)
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Vol. 6. Issue 3.
Pages 195-204 (May - June 2000)
PALESTRA/LECTURE
Open Access
Suberose: mais do que uma pneumonite de hipersensibilidade…
Suberosis: more than hypersensitivity pneumonitis…
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J.C. Winck*, J. Luis Delgado**
* Serviço de Pneumologia, H.S.João e Faculdade de Medicina do Porto (Director: Prof Dr J Agostinho Marques)
** Serviço de Imunologia, H.S. João e Faculdade de Medicina do Porto (Director: Prof Dr JA Fleming Torrinha)
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RESUMO

A Pneumonite de Hipersensibilidade representa a forma de apresentação clínica mais frequente da Suberose. Contudo, o atingimento das vias aéreas nalguns destes casos, a par da ocorrência de um número crescente de formas obstrutivas, torna por vezes complexa a abordagem diagnóstica. Neste trabalho, descrevemos o envolvimento de algumas células e mediadores solúveis do Líquido de Lavagem Broncoalveolar na Suberose, procurando analisar alguns mecanismos etiopatogénicos da doença obstrutiva das vias aéreas e da Pneumonite de Hipersensibilidade.

REV PORT PNEUMOL 2000; VI (3): 195-104

Palavras chave:
Suberose
asma ocupacional
lavagem broncoalveolar
ABSTRACT

Hypersensitivity Pneumonitis is the most common clinical presentation or Suberosis. However, airway involvement in some of these cases, associated with the increasing number of obstructive syndromes, make diagnostic approach sometimes complex. In this work we describe the effector cells and mediators in Bronchoalveolar Lavage Fluid of Suberosis, analysing some of the ethiopathogenie mechanisms of airways obstructive disease and Hypersensitivity Pneumonitis.

REV PORT PNEUMOL 2000; VI (3): 195-204

Key-words:
Suberosis
occupational asthma
broncoalveolar lavage
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BIBLIOGRAFIA
[1.]
J.W. Gurney.
Hypersensitivity Pneumonitis.
Radiol Clin N Am, 30 (1992), pp. 1219-1230
[2.]
R. Ávila, J.M.G. Lucas, A.T. Araújo, J. Lacey, M.C. Heitor, E.M. Mendes, I. Maulide, B. Almeida, M.H. Campos, R.A. Marques, A.P. Menezes, J. Ramada, M.G. Villar, M.L. Carvalheira, M.M.B. Perdigão, M.C. Póvoa.
Estudo epidemiológico da doença respiratória dos trabalhadores da indústria da cortiça.
O Médico, 68 (1973), pp. 257
[3.]
A. Carvalho, J.M. Sá, F.F. Rodrigues, J. Seada, M.C. Brito, J.C. Caminha, J. Cunha, J.P. Braga, A. Veiga De Macedo, J.L. Delgado, C. Cerveira, F. Campilho, J.F. Torrinha.
Manifestações broncopulmonares em operários inalando poeiras de cortiça.
O Médico, 115 (1986), pp. 311-318
[4.]
J.C. Pimentel, R. Ávila.
Respiratory disease in workers in the cork industry (Suberosis): new trends and diagnostic possibilities.
Thorax, 28 (1973), pp. 409-432
[5.]
R. Avila, J. Lacey.
The role of Penicillium frequentans in Suberosis (Respiratory Disease in workers in the cork industry).
Clinical Allergy, 4 (1974), pp. 109-117
[6.]
WINCK JC, SHIANG T, SAPAGE JM, DELGADO L, VANZELLER M, TORRES S. Suberose: Clínica e Fisiopatologia. Rev Port Pneumo II (6 Supl. I): 41-46.
[7.]
J.M. Sapage, L. Delgado, S. Torres, P. Vicente, J.C. Winck, P. Rodrigues, J.I. Ribeiro.
Suberose: contribute da lavagem broncoalvcolar no diagnóstico da patologia respiratória nos trabalhadores da Indústria da Cortiça.
Arq SPPR, 9 (1992), pp. 321-327
[8.]
DELGADO L. Imunologia da Suberose. Rev Port Pneumol II (6 Supl. I): 23-40.
[9.]
J. Rodrigues, Moreira Da Silva JP, J.L. Delgado, M.G. Castel-Branco.
Pneumonitcs de Hipersensibilidade.
Rev Port Imunoalergol, I (1992), pp. 34-39
[10.]
G. Semenzato, L. Trantin, R. Zambello, C. Agostini, A. Cipriani, G. Marcer.
Different types of cytotoxic lymphocytes recovered from the lungs of patients with Hypersensitivity Pneumonitis.
Am Rev Respir Dis, 137 (1988), pp. 70-74
[11.]
G. Semenzato, L. Bjermer, U. Costabel, P.L. Haslam, D. Olmeri.
Extrinsic Allergic Alveolitis.
Eur Respir J, 3 (1990), pp. 945-946
[12.]
L. Delgado, J.P. Ramos, J.C. Winck, C. Cuesta, Torrinha Já Fleming.
Cytotoxic lymphocytes in Hypersensitivity Pneumonitis.
Clinical Experimental Allergy, 23 (1993), pp. 25
[13.]
L. Delgado, M.C.T. Palmares, J.C. Winck, P. Silveira, J.M. Sapage, J.A.F. Torrinha.
Quantification of Penicillium frequentans specific IgG in cork worker’s pneumonitis (Suberosis), using a new solid phase the Immuno­CAP.
J Allergy Clin Immunol, 97 (1997),
[14.]
L.G. Arlian, D.L. Vyszeskj-Moher, S.G. Johansson, M. Van Hage-Hamsten.
Allergenic characterization of Thyrophagus putrescentiae using sera from occupationally exposed farmers.
Ann Allergy Asthma Immunol, 79 (1997), pp. 525-529
[15.]
M.J. Collof, T.G. Merrett, J. Merrett, C. Mcsharry, G. Boyd.
Feather mites are potentially an important source of allergens for pigeon and budgerigar keepers.
Clin Exp Allergy, 27 (1997), pp. 60-67
[16.]
P. Bradding, J.Á. Roberts, M. Britte, S. Montefort, R. Djukanovic, R. Mueller.
Interleukin 4,5,6 and Tumor Necrosis Factor alfa in normal and asthmatic airways: evidence for human mast cell as a source of these cytokines.
Am J Respir Cell Mol Biol, 10 (1994), pp. 471-480
[17.]
R. Pesci, G. Bertorelli, M. Gabrieli, D. Olivieri.
Mast cells in fibrotic lung disorders.
Chest, 103 (1993), pp. 989-996
[18.]
L. Delgado, C. Cuesta, J.C. Winck, J.M. Sapage, E.S.Á. Moura, Torrinha Já Fleming.
La Suberosis: implicacion de los mastocitos broncoalveolares en la genesis de la afectacion intersticial.
Arch Bronconeumol, 12 (1999),
[19.]
R.M. Cherniack.
Physiologic alterations in intersticial lung disease.
Interstitial Lung Disease, 2 Edicción, pp. 79-90
[20.]
R. Azevedo-Bernarda.
Fibroses intersticiais do pulmlão. Pulmão Profundo.
Estruturas e Mecanismos, pp. 125-147
[21.]
H.B. Richerson, I.L. Bernstein, G. Fink, G.W. Hunninghake, H.S. Novey, C.E. Reed, J. Salvaggio, M.R. Schuyler, H.J. Schwartz, D.J. Stechschulte.
Guidelines for the Clinical Evaluation of Hypersensitivity Pneumonitis.
J Allergy Clin Immunol, 84 (1989), pp. 839-844
[22.]
C. Rose, T.E. King.
Controversies in Hypersensitivity Pneumonitis.
Am Rev Respir Dis, 145 (1992), pp. 1-2
[23.]
K. Kaukonen, J. Savolainen, M. Viander, M. Kotimaa, E.O. Terho.
IgG and IgA subclass antibodies against Aspergillus umbrosus in farmer’s lung disease.
Clin Exp Allergy, 23 (1993), pp. 851-856
[24.]
E. Fournier, A.B. Tonnel, P.H. Gosset, B. Wallaert, J.C. Ameisen, C. Voisin.
Early Neutrophil Aivcolitis after antigen Inhalation in Hypersenstivity Pneumonitis.
Chest, 88 (1985), pp. 563-566
[25.]
Y. Sibille, H.Y. Reynolds.
Macrophages and Polymorphonuclear Neutrophils in Lung Defense and Injury.
Am Rev Respir Dis, 141 (1990), pp. 471-501
[26.]
C. Kroegel, J.Á. Warner, J.C. Virchow, H. Matthys.
Pulmonary immune cells in health and disease: the eosinophil leucocyte (Part II).
Eur Respir J, 7 (1994), pp. 743-760
[27.]
J. Bousquet, P. Chanez, J.Y. Lacoste, G. Barneon, N. Chavanian, I. Enander, P. Venge, S. Ahlstedt, J. Simony-Lafontaine, P. Godard, F.B. Michel.
Eosinopihilic inflammation in asthma.
N Engl J Med, 323 (1990), pp. 1033-1039
[28.]
A.M. Bentley, S.R. Durham, A.B. Kay.
Comparison of the Immunopathology of extrinsic, intrinsic and occupational asthma.
J Invest Allergol Clin Immunol, 4 (1994), pp. 222-232
[29.]
M. Kraft, R. Djukanovic, S. Wilson, S.T. Holgate, R.J. Martin.
Alveolar Tissue Inflammation in Asthma.
Am J Respir Crit Care Med, 154 (1996), pp. 1505-1510
[30.]
J.C. Winck, J.M. Sapage, S. Torres, M. Vanzeller, M.C. Palmares, J.L. Delgado.
Workrelated changes in peak expiratory flow in cork worker’s respiratory disease (Suberosis).
J Allergy Clin Jmmunol, (1999),
[31.]
J.C.H. Dalphin, D. Pernet, A. Dubiez, D. Debieuvre, H. Allemand, A. Depierre.
Etiologic factors of chronic Bronchitis in Dairy Farmers.
Chest, 103 (1993), pp. 417-421
[32.]
R. Erkinjuntti-Pekannen, H. Rytkonen, J.I. Kokka-Rinen, H.O. Tukiainen, K. Partanen, E. Terho.
Long-term risk of Emphysema in patients with Farmer’s Lung and Matched controls.
Am J Respir Crit Care Med, 158 (1998), pp. 662-665
[33.]
M.C. Alvim Ferraz.
Trans formação da Cortia.Prevenção da Suberose.
Rev Port Pneumol, II (1996), pp. 77-90
[34.]
M. Selman-Lama, R. Pérez-Padilla.
Airflow Obstruction and Airway lesions in Hypersensitivity Pneumonitis.
Clin Chest Med, 14 (1993), pp. 699-714
[35.]
J.C. Winck, M. Vanzeller, J.M. Sapage, S. Torres, J.L. Delgado.
Formas agudas de Suberose: evolução clínica, funcional e do líquido de lavagem broncoalveolar.
Rev Port Pneumol, IV (1998), pp. P1
Copyright © 2000. Sociedade Portuguesa de Pneumologia/SPP
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