Respostas das citocinas T 2 desencadeadas por Mycobacterium tuberculosis virulento nos doentes com tuberculose pulmonar em estado avançado

ARTIGO ORIGINAL/ORIGINAL ARTICLE

Type 2 cytokine responses elicited by virulent Mycobacterium tuberculosis in advanced tuberculosis patients

Diane J. Ordway1, Maria J. Arroz2, Mónica S. Freire3, Hazel M. Dockrell4, Fernando A. Ventura5

1 Doutorada e Investigadora no projecto de Investigação em Imunologia das Micobactérias, Centro de Malária e Outras Doenças Tropicais, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Junqueira, 96, 1349-008 Lisboa, Portugal.

2 Assistente Hospitalar Graduada de Patologia Clínica; Responsável pelo Laboratório de Hematologia e de Citometria de Fluxo do Serviço de Patologia Clínica do Hospital Egas Moniz, Rua da Junqueira 126, 1349-019 Lisboa, Portugal; Assistente Convidada de Imunologia da Faculdade de Ci_ncias Médicas da Universidade Nova de Lisboa.

3 Estudante do último ano de Engenharia Biotecnológica e Bolseira do projecto de investigação denominado "Eurostandards", financiado pela Uni_o Europeia, Hospital Egas Moniz, Rua da Junqueira 126, 1349-019 Lisboa, Portugal, e no Centro de Malária e Outras Doenças Tropicais, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Junqueira, 96, 1349-008 Lisboa, Portugal.

4 Assistente na Unidade de Imunologia da London School of Hygiene &Tropical Medicine, Department of Infectious and Tropical Medicine, Immunology Unit, Keppel Street, London, WC1E 7HT, UK

5 Coordenador da Comissão Nacional de Luta Contra a SIDA, Palácio Bensaúde Estrada da Luz, 153, 1600 Lisboa, Portugal; Responsável do projecto de Investigação em Imunologia das Micobactérias, Centro de Malária e Outras Doenças Tropicais, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Junqueira, 96, 1349-008 Lisboa, Portugal; Assistente Hospitalar de Infecciologia, Serviço de Doenças Infecciosas e Parasitárias, Hospital Egas Moniz, Rua da Junqueira 100, 1349-008 Lisboa, Portugal; Professor Regente da Disciplina de Doenças Infecciosas e Parasitárias da Faculdade de Ciências Médicas da Universidade Nova de Lisboa.

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ISSN: 08732159
Original language: Portuguese

DOI:10.1016/S0873-2159(15)30829-1

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